Jerome J Maller and Chantal Reglade-Meslin
Mild to moderate traumatic brain injury (TBI) often results in diffuse axonal injury and post-traumatic amnesia,
with short- and long-term cognitive and neurological impairment. Whilst there are a variety of neuroimaging-based
computerized techniques by which to investigate longitudinal brain changes after brain insult, there are some which
can be appreciated by the naked eye from traditional T1-weighted structural magnetic resonance (MR) imaging
without the need for further image manipulation or analysis. In this article we review such regions with a focus on
the hippocampus and fornix based on longitudinal structural MR images from patients who have sustained a mild to
moderate TBI.