Yeong-Jang Lin, Hung-An Chen and Pei-Chih Chen
Neutropenic enterocolitis is a rare, life-threatening disease, characterized by fever and abdominal pain in the setting of neutropenia. It occurs most commonly in oncologic patients who are profoundly neutropenic as a result of cytotoxic chemotherapy. Neutropenic enterocolitis as a complication of medical therapy for rheumatoid arthritis (RA) has been rarely reported in literature. We describe a patient with RA who developed neutropenic enterocolitis as a complication of methotrexate therapy.