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Pharmacovigilance through big data | 55098

薬学および医薬品開発ジャーナル

概要

Pharmacovigilance through big data

Bernard M Y Cheung

I n Hong Kong 70% of inpatient care is in public hospitals and most acute emergencies are treated in public hospitals. consequently the maximum critical adverse drug reactions present to public hospitals. The Clinial statistics Analyais and Reporting gadget (CDARS) has been taking pictures prescribing and dispensing data, as well as hospital and clinic attendance statistics, in Hong Kong for over ten years. This real source of statistics can link clinical occasions, as a minimum the extreme ones, with dispensing statistics. There are 3 current examples of the way we used those statistics. first off, contaminiated batches of frequent valsartan had been recalled in 2018 and we monitored the each day admissions due to stroke in the entire of Hong Kong. happily, there has been now not the slightest sign of an abrupt upward push in stroke. Secondly, we studied drug-associated hypokalaemia (low plasma potassium) within the populace. Of around 25000 hospitalisations due to hypokalaemia over a ten-year length, around 5000 were because of diuretics, one third of which had been due to indapamide used for the remedy of hypertension. finally, we studied the occurrence and hazard elements for vancomycin-prompted acute kidney damage.

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